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Cover Page Articles
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Research Articles


1. Mondal A, Chakraborty A, Nandi S, Singh V, Kamat SS, Das C*. 2026. Transcription Factor 19 Modulates Fatty Acid Elongation and Unfolded Protein Response to Attenuate Palmitic Acid-Induced Hepatic Dysfunction. Nature Communications. In Press. JIF: 17.2.

2. Mondal A, Nandi S, Mandal B, Banerjee I, Ddoza Hazari MWA, Das C*. 2025. Protocol for 3D tumor spheroid generation, immunostaining, and imaging through comparative approaches. STAR Protocols. 6(4):104168. JIF: 1.3.

3. Nandi S, Mondal A, Sarkar I, Hazari MWAD, Banerjee I, Ghosh S, Roy H, Banerjee A, Bandyopadhyay A, Aich S, Sengupta S, Chatterjee S, Das C*. 2025. The Hypoxia-Induced Chromatin Reader ZMYND8 Drives HIF-Dependent Metabolic Rewiring in Breast Cancer. Journal of Biological Chemistry. 301(10):110680. JIF: 4.0.

4. Mondal A, Nandi S, Singh V, Chakraborty A, Banerjee I, Sen S, Gadad SS, Roy S, Kamat SS, Das C*. 2025. TCF7L2 Regulates Fatty Acid Chain Elongase HACD3 during Lipid-Induced Stress. Biochemistry. 64(8):1828–1840. Accepted for Supplementary Cover Page Publication. JIF: 3.0.

5. Adhikari S, Ghosal M, Kabiraj A, Senapati D*, Das C*. 2024. Protocol for evaluating extracellular matrix stiffness post-decellularization of triple-negative breast cancer cells using atomic force microscopy. STAR Protocols. 5(4):103460. JIF: 1.3.

6. Singh V, Mondal A, Adhikary S, Mondal P, Shirgaonkar N, DasGupta R, Roy S, Das C*. 2024. UBR7 E3 Ligase suppresses IFN-β mediated immune signaling by targeting Sp110 in HBV-induced HCC. ACS Infectious Diseases. 10(11):3775–3796. Accepted for Cover Page Publication. JIF: 3.8.

7. Adhikari S, Singh V, Nandi S, Ghoshal M, Sundar Raj N, Khanna J, Bhattacharya A, Kabiraj A, Mondal A, Vasudevan M, Senapati D, Roy H, Sengupta K, Notani D, Das C*. 2024. UBR7 in concert with EZH2 inhibits the TGF-β signalling leading to extracellular matrix remodelling. Cell Reports. 43(7):114394. JIF: 9.995.

8. Guha D, Singh V, Nandi S, Ramos EI, Gadad SS, Das C*. 2024. ZMYND8 Is a Regulator of Sonic Hedgehog Signaling in ATRA-Mediated Differentiation of Neuroblastoma Cells. Biochemistry. 63(12):1534–1542. Accepted for Supplementary Cover Page Publication. JIF: 3.0.

9. Adhikary S, Singh V, Choudhari R, Yang B, Adhikari S, Ramos EI, Chaudhuri S, Roy S, Gadad SS*, Das C*. 2022. ZMYND8 suppresses MAPT213 LncRNA transcription to promote neuronal differentiation. Cell Death & Disease. 13(9):766. JIF: 9.8.

10. Sengupta I, Mondal P, Sengupta A, Mondal A, Singh V, Adhikari S, Dhang S, Roy S, Das C*. 2022. Epigenetic regulation of Fructose-1,6-Bisphosphatase 1 by host transcription factor Speckled 110 kDa during Hepatitis B Virus infection. FEBS Journal. 289(21):6694–6713. JIF: 4.2.

11. Srivastava DK, Gunjan S, Das C, Seshadri V, Roy S. 2021. Structural insights into histone chaperone Asf1 and its characterization from Plasmodium falciparum. Biochemical Journal. 478(5):1117–1136.

12. Mondal P, Gadad SS, Adhikari S, Ramos EI, Sen S, Prasad P, Das C*. 2021. TCF19 and p53 Regulate Transcription of TIGAR and SCO2 in HCC for Mitochondrial Energy Metabolism and Stress Adaptation. FASEB Journal. 35(9):e21814. JIF: 4.2.

13. Mukherjee S, Adhikary S, Gadad SS, Mondal P, Sen S, Choudhari R, Singh V, Adhikari S, Mandal P, Chaudhuri S, Sengupta A, Lakshmanaswamy R, Chakrabarti P, Roy S, Das C*. 2020. Suppression of poised oncogenes by ZMYND8 promotes chemo-sensitization. Cell Death & Disease. 11(12):1073. JIF: 9.8.

14. Sanyal S, Mondal P, Sen S, Sengupta Bandyopadhyay S, Das C*. 2020. SUMO E3 ligase CBX4 regulates hTERT-mediated transcription of CDH1 and promotes breast cancer cell migration and invasion. Biochemical Journal. 477(19):3803–3818. JIF: 4.3.

15. Karmakar D, Maity J, Mondal P, Shyam Chowdhury P, Sikdar N, Karmakar P, Das C, Sengupta S. 2020. E2F5 promotes prostate cancer cell migration and invasion through regulation of TFPI2, MMP-2 and MMP-9. Carcinogenesis. 41(12):1767–1780.

16. Mondal P, Sen S, Klein BJ, Tiwary N, Gadad SS, Kutateladze TG, Roy S, Das C*. 2020. TCF19 promotes cell proliferation through binding to the histone H3K4me3 mark. Biochemistry. 59(4):389. Accepted for Supplementary Cover Page Publication. JIF: 3.0.

17. Mukherjee S, Sen S, Adhikary S, Sengupta A, Mandal P, Dasgupta D, Chakrabarti P, Roy S, Das C*. 2020. A novel role of tumor suppressor ZMYND8 in inducing differentiation of breast cancer cells through its dual histone binding function. Journal of Biosciences. 45:2.

18. Adhikary S, Chakravarti D, Terranova C, Sengupta I, Maitituoheti M, Dasgupta A, Srivastava DK, Ma J, Raman AT, Tarco E, Sahin AA, Bassett R, Yang F, Tapia C, Roy S*, Rai K*, Das C*. 2019. Atypical Plant Homeodomain of UBR7 Functions as an H2BK120Ub Ligase and Breast Tumor Suppressor. Nature Communications. 10(1):1398. JIF: 16.1.

19. Chakraborty B, Mondal P, Gajendra P, Mitra M, Das C, Sengupta S. 2018. Deciphering genetic regulation of CD14 by SP1 through characterization of peripheral blood mononuclear transcriptome of P. falciparum and P. vivax infected malaria patients. EBioMedicine. 37:442–452.

20. Ray T, Kar D, Pal A, Mukherjee S, Das C, Pal A. 2018. Molecular targeting of breast and colon cancer cells by PAR1 mediated apoptosis through a novel pro-apoptotic peptide. Apoptosis. 23(11–12):679–694.

21. Sau A, Sanyal S, Bera K, Sen S, Mitra AK, Pal U, Chakraborty PK, Ganguly S, Satpati B, Das C*, Basu S*. 2018. DNA Damage and Apoptosis Induction in Cancer Cells by Chemically Engineered Thiolated Riboflavin Gold Nanoassembly. ACS Applied Materials & Interfaces. 10(5):4582–4589.

22. Sengupta I, Das D, Singh SP, Chakravarty R, Das C*. 2017. Host transcription factor Speckled 110 kDa (Sp110), a nuclear body protein, is hijacked by Hepatitis B virus protein X for viral persistence. Journal of Biological Chemistry. 292(50):20379–20393.

23. Sen S, Sanyal S, Srivastava DK, Dasgupta D, Roy S, Das C*. 2017. Transcription factor 19 regulates gluconeogenesis in concert with the nucleosome-remodelling-deacetylase complex via histone 3 lysine 4 trimethylation recognition. Journal of Biological Chemistry. 292(50):20362–20378. Accepted for Cover Page Publication.

24. Basu M, Sengupta I, Khan W, Srivastava DK, Chakrabarti P, Roy S, Das C*. 2017. Dual histone reader ZMYND8 inhibits cancer cell invasion by positively regulating epithelial genes. Biochemical Journal. 474(11):1919–1934.

25. Goswami S, Sanyal S, Chakraborty P, Das C*, Sarkar M*. 2017. Interaction of a Common Painkiller Piroxicam and Copper-piroxicam with Chromatin Causes Structural Alterations Accompanied by Modulation at the Epigenomic/Genomic level. Biochimica et Biophysica Acta – General Subjects.

26. Basu M, Khan MW, Chakrabarti P, Das C*. 2017. Chromatin reader ZMYND8 is a key target of all trans retinoic acid-mediated inhibition of cancer cell proliferation. Biochimica et Biophysica Acta – Gene Regulatory Mechanisms. 1860(4):450–459.

27. Das D, Sengupta I, Sarkar N, Pal A, Saha D, Bandopadhyay M, Das C, Narayan J, Singh SP, Chakrabarti S, Chakravarty R. 2017. Anti-hepatitis B virus response of imiquimod based toll like receptor 7 ligand in HBV-positive human hepatocellular carcinoma cell line. BMC Infectious Diseases. 17(1):76.

28. Das D, Sarkar N, Sengupta I, Pal A, Saha D, Bandopadhyay M, Das C, Narayan J, Singh SP, Chakravarty R. 2016. Anti-viral role of toll like receptor 4 in hepatitis B virus infection: An in vitro study. World Journal of Gastroenterology. 22(47):10341–10352.

29. Bandopadhyay M, Sarkar N, Datta S, Das D, Pal A, Panigrahi R, Banerjee A, Panda CK, Das C, Chakrabarti S, Chakravarty R. 2016. Hepatitis B virus X protein mediated suppression of miRNA-122 expression enhances hepatoblastoma cell proliferation through cyclin G1-p53 axis. Infectious Agents and Cancer. 11:40.

30. Banerjee A, Sanyal S, Dutta S, Chakraborty P, Das PP, Jana K, Vasudevan M, Das C*, Dasgupta D*. 2016. The plant alkaloid chelerythrine binds to chromatin, alters H3K9Ac and modulates global gene expression. Journal of Biomolecular Structure and Dynamics. 35(7):1491–1499.

31. Adhikary S, Sanyal S, Basu M, Sengupta I, Sen S, Srivastava DK, Roy S*, Das C*. 2016. Selective Recognition of H3.1K36 dimethylation/H4K16 acetylation facilitates the regulation of ATRA-responsive genes by putative chromatin reader ZMYND8. Journal of Biological Chemistry. 291:2664–2681.

32. Chakrabarti R, Sanyal S, Ghosh A, Bhar K, Das C*, Siddhanta A*. 2015. Phosphatidylinositol 4-phosphate 5-kinase 1-alpha modulates ribosomal RNA gene silencing through its interaction with histone H3 lysine 9 trimethylation and heterochromatin protein HP1-alpha. Journal of Biological Chemistry. 290:20893–20903.

33. Banerjee A, Sanyal S, Majumder P, Chakraborty P, Jana K, Das C*, Dasgupta D*. 2015. Recognition of chromatin by the plant alkaloid, ellipticine as a dual binder. Biochemical and Biophysical Research Communications. 462:352–357.

34. Kulkarni KK, Bankar KG, Shukla RN, Das C, Banerjee A, Jana K, Dasgupta D, Vasudevan M. 2014. Global gene expression profiling data analysis reveals key gene families and biological processes inhibited by Mithramycin in sarcoma cell lines. Genomics Data. 3:8–14.

35. Banerjee A, Sanyal S, Kulkarni KK, Jana K, Roy S, Das C*, Dasgupta D*. 2014. Anticancer drug mithramycin interacts with core histones: an additional mode of action of the DNA groove binder. FEBS Open Bio. 4:987–995.

36. Das C, Roy S, Namjoshi S, Malarkey CS, Jones DN, Kutateladze TG, Churchill ME, Tyler JK. 2014. Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation. Proceedings of the National Academy of Sciences USA. 111(12):E1072–E1081.

37. Banerjee A, Majumder P, Sanyal S, Singh J, Jana K, Das C*, Dasgupta D*. 2014. The DNA intercalators ethidium bromide and propidium iodide also bind to core histones. FEBS Open Bio. 4:251–259.

38. Feser J, Truong D, Das C, Carson JJ, Kieft J, Harkness T, Tyler JK. 2010. Elevated histone expression promotes lifespan extension. Molecular Cell. 39(5):724–735.

39. Das C, Gadad SS, Kundu TK. 2010. Human positive coactivator 4 controls heterochromatinization and silencing of neural gene expression by interacting with REST/NRSF and CoREST. Journal of Molecular Biology. 397(1):1–12.

40. Ransom M, Williams SK, Dechassa ML, Das C, Linger J, Adkins M, Liu C, Bartholomew B, Tyler JK. 2009. FACT and the proteasome promote promoter chromatin disassembly and transcriptional initiation. Journal of Biological Chemistry. 284(35):23461–23471.

41. Das C, Lucia MS, Hansen KC, Tyler JK. 2009. CBP/p300-mediated acetylation of histone H3 on Lysine 56. Nature. 459(7243):113–117.

42. Selvi BR, Pradhan SK, Shandilya J, Das C, Sailaja BS, Shankar GN, Gadad SS, Dasgupta D, Kundu TK. 2009. Putative anticancer therapeutic, Sanguinarine interacts with chromatin; modulates epigenetic modifications and chromatin transcription. Chemistry & Biology. 16(2):203–216.

43. Kishore AH, Batta K, Das C, Agarwal S, Kundu TK. 2007. p53 Regulates Its Own Activator – Transcriptional Coactivator PC4: A New p53 Responsive Gene. Biochemical Journal. 406(3):437–444.

44. Mantelingu K, Kishore AH, Balasubramanyam K, Kumar GV, Altaf M, Swamy SM, Selvi BR, Das C, Narayana C, Rangappa KS, Kundu TK. 2007. Activation of p300 histone acetyltransferase by small molecules altering enzyme structure: Probed by Surface Enhanced Raman Spectroscopy. Journal of Physical Chemistry B. 111(17):4527–4534.

45. Das C, Hizume K, Batta K, Kumar BR, Gadad SS, Ganguly S, Lorain S, Verreault A, Sadhale PP, Takeyasu K, Kundu TK. 2006. Transcriptional Coactivator PC4, A Chromatin-associated Protein, Induces Chromatin Condensation. Molecular and Cellular Biology. 26(22):8303–8315. 

Reviews

  1. 1. Banerjee I, Mondal A, Kamat SS, Das C*. 2026. Metabolites with a message: impacts on epigenetics and implications for epimetabopathies. EMBO Reports. In Press. JIF: 6.0.

  2. 2. Hazari MW, Nandi S, Das C*. 2026. Epigenetic rewiring and T cell exhaustion in HBV-induced HCC with implications for precision therapies. Biochemical and Biophysical Research Communications. 815:153656. JIF: 2.2.

  3. 3. Dasgupta A, Nandi S, Gupta S, Roy S, Das C*. 2024. To Ub or not to Ub: The epic dilemma of histones that regulate gene expression and epigenetic cross-talk. Biochimica et Biophysica Acta – Gene Regulatory Mechanisms. 1867(3):195033. JIF: 3.1.

  4. 4. Das C*, Bhattacharya A, Adhikari S, Mondal A, Mondal P, Adhikary S, Roy S, Ramos K, Yadav K, Tainer JA*, Pandita TK*. 2024. A prismatic view of the epigenetic-metabolic regulatory axis in breast cancer therapy resistance. Oncogene. 43(23):1727–1741. JIF: 7.4.

  5. 5. Singh V, Nandi S, Ghosh A, Mukherjee S, Roy S, Das C*. 2024. Epigenetic reprogramming of T cells: Unlocking New Avenues for Cancer Immunotherapy. Cancer and Metastasis Reviews. 43(1):175–195. JIF: 10.1.

  6. 6. Das C*, Adhikari S, Bhattacharya A, Chakraborty S, Mondal P, Yadav SS, Adhikary S, Hunt CR, Yadav K, Pandita S, Roy S, Tainer JA, Ahmed Z, Pandita TK*. 2023. Epigenetic-Metabolic Interplay in the DNA Damage Response and Therapeutic Resistance of Breast Cancer. Cancer Research. 83(5):657–666. JIF: 16.6.

  7. 7. Adhikari S, Bhattacharya A, Adhikary S, Singh V, Gadad SS, Roy S, Das C*. 2022. The paradigm of drug resistance in cancer: an epigenetic perspective. Bioscience Reports. 42(4):BSR20211812.

  8. 8. Mondal A, Bhattacharya A, Singh V, Pandita S, Bacolla A, Pandita RK, Tainer JA, Ramos KS, Pandita TK*, Das C*. 2022. Stress responses as master keys to epigenomic changes in transcriptome and metabolome for cancer etiology and therapeutics. Molecular and Cellular Biology. 42(1):e0048321. JIF: 4.1.

  9. 9. Adhikary S, Roy S, Chacon J, Gadad SS, Das C*. 2021. Implications of enhancer transcription and eRNAs in cancer. Cancer Research. 81(16):4174–4182. JIF: 16.6.

  10. 10. Sedano MJ, Harrison AL, Zilaie M, Das C, Choudhari R, Ramos E, Gadad SS. 2020. Emerging Roles of Estrogen-Regulated Enhancer and Long Non-Coding RNAs. International Journal of Molecular Sciences. 21(10):3711.

  11. 11. Sen S, Das C*. 2018. Managing the sugar factory: A new feather in the cap for nuclear factor Y. Journal of Biological Chemistry. 293(20):7905–7906.

  12. 12. Das C, Tyler JK. 2013. Histone exchange and histone modifications during transcription and aging. Biochimica et Biophysica Acta. 1819(3–4):332–342.

  13. 13. Das C, Tyler JK, Churchill ME. 2010. The histone shuffle: histone chaperones in an energetic dance. Trends in Biochemical Sciences. 35(9):476–489.

  14. 14. Das C, Kundu TK. 2005. Transcriptional regulation by the acetylation of nonhistone proteins in humans—a new target for therapeutics. IUBMB Life. 57(3):137–149.

Book Chapters

  1. 1. Mondal A, Das C*. 2026. Epigenetic regulation of fatty acid chain elongation in MAFLD and its implications in the liver-brain axis dysfunction. Methods in Enzymology. 734:151–171.

  2. 2. Mandal B, Banerjee I, Hazari MWAD, Mondal A, Das C*. 2025. ECM-Lamin Crosstalk in the Regulation of Genomic Stability. Subcellular Biochemistry. Springer Nature. 115:163–184.

  3. 3. Nandi S, Mondal A, Ghosh A, Mukherjee S, Das C*. 2023. Lnc-ing epigenetic mechanisms with autophagy and cancer drug resistance. Advances in Cancer Research. Elsevier. 160:133–203.

  4. 4. Adhikari S, Guha D, Mohan C, Mukherjee S, Tyler JK, Das C*. 2022. Reprogramming carbohydrate metabolism in cancer and its role in regulating the tumor microenvironment. Subcellular Biochemistry: Metabolism and Epigenetic Regulation: Implications in Cancer. Springer Nature. 100:3–65.

  5. 5. Mondal P, Tiwary N, Sengupta A, Dhang S, Roy S, Das C*. 2022. Epigenetic reprogramming of the Glucose metabolic pathways by the Chromatin effectors during Cancer. Subcellular Biochemistry: Metabolism and Epigenetic Regulation: Implications in Cancer. Springer Nature. 100:269–336.

  6. 6. Mukherjee S, Adhikary S, Roy S, Das C*. 2017. Noncoding RNAs as chromatin scaffold of histone modification complexes in cancer. In Cancer and Non-coding RNAs, Translational Epigenetics Series. Elsevier. 1:330–352.

  7. 7. Kumari S, Das C, Sikder S, Kumar M, Bachu M, Ranga U, Kundu TK. 2015. Identification and characterization of nonhistone chromatin proteins: human positive coactivator 4 as a candidate. Methods in Molecular Biology: Chromatin Protocols. 1288:245–272.

  8. 8. Batta K, Das C, Gadad S, Shandilya J, Kundu TK. 2007. Reversible acetylation of nonhistone proteins: Role in cellular functions and diseases. Subcellular Biochemistry: Chromatin and Disease. 41:193–212.

DAE - Saha Institute of Nuclear Physics, Kolkata, West Bengal, India

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